During the first 4 to 12 years of ART, people with chronic HBV gained significantly more CD4 cells than people without HBV infection. Despite that advantage, people with chronic HBV infection had a 68% higher risk of AIDS or death than did HBV-negative people (hazard ratio 1.68, 95% confidence interval 1.05 to 2.68), and people with resolved HBV infection had a 61% higher risk of AIDS or death (hazard ratio 1.61, 95% confidence interval 1.15 to 2.25).
The researchers propose that “CD4 cell count reconstitution after [ART initiation] and the risk of an AIDS event or death after [ART initiation] may be associated with hepatitis B status.”
Reprinted by permission from BlackAIDS.org.
Risk Of AIDS Higher With Hep B Infection was originally published on blackdoctor.org
