“It’s so nice to be here,” he said.
Other performers included Kings of Leon and Alicia Keys, whose set included “No One” and “Empire State of Mind.”
“I believe if we don’t care about each other, who will?” the singer said. “Help me celebrate tonight so we never forget.”
Wonder also had a touching moment when he sang John Lennon’s “Imagine” and encouraged the audience to lobby for more gun laws.
“Can you believe blind people have guns?” he said. “Let’s keep it real. Ridiculous.”
Last year’s Global Citizen Festival featured Neil Young and Crazy Horse, Foo Fighters and The Black Keys. The festival’s nonprofit partners pledged $1.3 billion in new fundraising commitments last year.
Wonder, who played the piano and harmonica, was joined onstage by R&B singers Maxwell and Janelle Monae.
“I can’t believe this is happening,” Maxwell gushed when singing “Superstition.”